Response of hypertension in chronic kidney patients submitted to resistance and aerobic training: a narrative review
Abstract
Background: Chronic Kidney Disease (CKD) is characterized by the progressive loss of kidney function, with or without morphological changes in the kidneys. Hypertension is a potential risk factor for the onset and worsening of the disease and it has gained attention from researchers and specialists due to the increase in adverse cardiovascular events during treatment. Aim: this work aims to carry out a review on the effects of resistance training and aerobic training on hypertension in Intradialytic chronic renal patients. Materials and Methods: The terms ("Chronic Kidney Disease") AND (Hypertension)) AND ("Aerobic Training") OR ("Resistance Training")) were searched in the PUBMED and Web of Science databases. Only original articles with humans with chronic kidney disease, hypertension, who underwent to a physical exercise program were accepted. Apenas artigos originais, com humanos doentes renais crônicos, com hipertensão, submetidos ao exercício físico formam aceitos.Results: 20 articles were found, however, 17 were excluded by the exclusion criteria and 3 were considered eligible. The selected studies provide data from 286 patients. Discussion: There are a variety of studies that prove the benefits of physical exercise for the health of a general population and there is little evidence about the role of exercise on hypertension in patients with CKD, but they all agree that staying physically active even with the diagnosis of the disease, it positively assists in the treatment, decreasing the mortality and morbidity rate, improving cardiovascular capacity, among others. Conclusion: the practice of aerobic and resistance exercises in hypertensive chronic renal patients helps in the acute control of blood pressure.
References
-Alcalde, P. R.; Kirsztajn, G. M. Gastos do Sistema Único de Saúde Brasileiro com doença renal crônica. Brazilian Journal of Nephrology. Vol. 40. Núm. 2. p. 122-129. 2018.
-Barcellos, F.C.; Del Vecchio, F.B.; Reges, A.; Mielke, G.; Santos, I.S.; Umpierre, D., Bohlke, M.; Hallal, P.C. Exercise in patients with hypertension and chronic kidney disease: a randomized controlled trial. Journal of human hypertension. Vol. 32. Núm. 6. p.397-407. 2018.
-Blumenthal, J.A.; Babyak, M.A.; Moore, K.A.; Craighead, W.E.; Herman, S.; Khatri, P.; Waugh, R.; Napolitano, M.A.; Forman, L.M.; Appelbaum, M.; Doraiswamy, P.M.; Effects of exercise training on older patients with major depression. Archives of internal medicine. Vol. 159. Núm.19. p. 2349-2356. 1999.
-Brito, L.; Peçanha, T.; Fecchio, R.; Rezende, R.; Sousa, P.; Silva Junior, N.; Abreu, A.; Silva, G.; Mion Junior, D.; Hallwill, J.; Forjaz, C. Morning vs evening aerobic training effects on blood pressure in treated hypertension. Medicine & Science in Sports & Exercise. Vol. 51. Núm. 4. p. 653-662. 2018.
-Brum, P. C.; Forjaz, C. L. M.; Tinucci, T.; Negrão, C. E. Adaptações agudas e crônicas do exercício físico no sistema cardiovascular. Rev Paul Educ Fís. Vol. 18. Núm. 1. p. 21-31. 2004.
-Chodzko-Zajko, W.J.; Proctor, D.N.; Singh, M.A.F.; Minson, C.T.; Nigg, C.R.; Salem, G.J.; Skinner, J.S. Exercise, and physical activity for older adults. Medicine & science in sports & exercise. Vol. 41. Núm.7. p. 1510-1530. 2009.
-Corrêa, H.L.; Neves, R.V.P.; Deus, L.A.; Maia, B.C.H.; Maya, A.T.; Tzanno-Martins, C.; Souza, M.K.; Silva, J.A.B.; Haro, A.S.; Costa, F.; Moraes, M.R. Low-load resistance training with blood flow restriction prevent renal function decline: The role of the redox balance, angiotensin 1-7 and vasopressin. Physiology & Behavior. Vol. 230. p.113295. 2021.
-Gaitonde, D. Y.; Cook, D. L.; Rivera. I. M. Chronic kidney disease: detection and evaluation. American family physician. Vol. 96. Núm. 12. p. 776-783. 2017.
-Headley, S.; Germain, M.; Wood, R.; Joubert, J.; Milch, C.; Evans, E.; Cornelius, A.; Brewer, B.; Taylor, B; Pescatello, L.S. Blood pressure response to acute and chronic exercise in chronic kidney disease. Nephrology. Vol. 22. Núm. 1. p.72-78. 2017.
-Howden, E.J.; Fassett, R.G.; Isbel, N.M.; Coombes, J.S. Exercise training in chronic kidney disease patients. Sports Medicine. Vol. 42. Núm. 6. p.473-488. 2012.
-Kakitapalli, Y., Ampolu, J. Madasu, S. D. Sai Kumar, M. L. S. Detailed review of chronic kidney disease. Kidney Diseases. Vol. 6. Núm. 2. p. 85-91. 2020.
-Kdigo. clinical practice guideline for management of blood pressure in CKD. Kidney International supplements. 2012.
-KDOQI. Clinical practice guidelines for cardiovascular disease in dialysis patients. Am J Kidney Dis. Vol. 45. Núm. 3. p. 1-153. 2005.
-Kokkinos, P.; Physical activity, health benefits, and mortality risk. International Scholarly Research Notices. 2012.
-Loenneke, J.P.; Wilson, J.M.; Wilson, G.J.; Pujol, T.J.; Bemben, M.G. Potential safety issues with blood flow restriction training. Scandinavian journal of medicine & science in sports. Vol. 21. Núm. 4. p.510-518. 2011.
-Marinho, A. W. G. B.; Penha, A. P.; Silva, M. T.; Galvão, T. F. Prevalência de doença renal crônica em adultos no Brasil: revisão sistemática da literatura. Cadernos Saúde Coletiva. Vol. 25. Núm. 3. p. 379-388. 2017.
-Pechter, Ü.; Ots, M.; Mesikepp, S.; Zilmer, K.; Kullissaar, T.; Vihalemm, T.; Zilmer, M.; Maaroos, J. Beneficial effects of water-based exercise in patients with chronic kidney disease. International Journal of Rehabilitation Research. Vol. 26. Núm. 2. p.153-156. 2003.
-Provenzano, M.; Coppolino, G.; Faga, T.; Garofalo, C.; Serra, R.; Andreucci, M. Epidemiology of cardiovascular risk in chronic kidney disease patients: the real silent killer. Reviews in cardiovascular medicine. Vol. 20. Núm. 4. p. 209-220. 2019.
-Rossi, A.; Dikareva, A.; Bacon, S.L.; Daskalopoulou, S.S. The impact of physical activity on mortality in patients with high blood pressure: a systematic review. Journal of hypertension. Vol. 30. Núm. 7. p.1277-1288. 2012.
-Rother, E.T. Revisão sistemática x revisão narrativa. Acta Paul Enferm. Vol. 20. Núm. 2. p.5-7. 2007.
-Saxena, S.; Van Ommeren, M.; Tang, K.C.; Armstrong, T.P. Mental health benefits of physical activity. Journal of Mental Health. Vol. 14. Núm. 5. p.445-451. 2005.
-Snyder, S.; Pendergraph, B. Detection and evaluation of chronic kidney disease. American family physician. Vol. 72. Núm. 9. p. 1723-1732. 2005.
-Wen, C.P.; Wai, J.P.M.; Tsai, M.K.; Yang, Y.C.; Cheng, T.Y.D.; Lee, M.C.; Chan, H.T.; Tsao, C.K.; Tsai, S.P.; Wu, X. Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study. The lancet. Vol. 378. Núm. 9798. p.1244-1253. 2011.
-Xie, Y.; Bowe, B.; Mokdad, Ali H.; Xian, H.; Yan, Y.; Li, T.; Maddukuri, G. Tsai, C.; Floyd, T.; Al-Aly, Z. Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016. Kidney international. Vol. 94. Núm. 3. p. 567-581. 2018.
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